How to take omeprazole for gastritis with high acidity


Anatomical information

The inner gastric lining is the first to come into contact with the gastrointestinal tract coming from the upper gastrointestinal tract, which means it is the first to be irritated by physical and chemical factors.
The mucosa contains many glands and cells that produce hydrochloric acid, gastromucoprotein, mucus, numerous enzymes, pepsinogen and hormones. All active substances together with mucus form gastric juice.

The active and physiological work of glands and cells creates optimal conditions for digestion, and also plays a protective and bactericidal role.

When infectious agents are introduced or exposed to irritating factors, the inner lining becomes inflamed, the glands and cells stop producing the necessary substances or begin to excessively secrete hydrochloric acid and pepsinogen.

An imbalance in the functioning of mucosal cells leads to a violation of acidity in the direction of its increase and digestive disorders. If these phenomena are observed, Omez can be an assistant in eliminating them.

About the drug

Two types of this drug are available: Omez and Omez D. The capsules of the first contain only omeprazole. They are transparent, colorless, with a pink lid, and contain 20 g of granules. Omez D contains not only omeprazole, but also domperidone. You can distinguish them by their appearance: they are white, with a purple lid. Preparations for preparing the solution are also produced. They do not contain tablets, but white powder.

This medicine prevents the basal cells of the stomach lining from producing hydrochloric acid. Acidity decreases, a person’s well-being improves. In addition, it has an antimicrobial effect. Thanks to this drug, an alkaline environment is created in which Helicobacter pylori cannot exist normally. Therefore, it is used both as a primary medicine and as part of treatment.

Contraindications for use

The main active ingredient is omeprazole. The chemical compound acts on parietal cells and inhibits the enzyme that is involved in the synthesis of gastric juice. Due to its pharmacological properties, the drug is used for the following conditions:

  • gastroesophageal and duodenogastric reflux, reflux gastritis;
  • therapy for Zollinger-Ellison syndrome;
  • reflux esophagitis in children over 24 months;
  • symptomatic treatment of heartburn and esophagitis;
  • systemic mastocytosis.

Before using the drug, you must read the information about the drug. Instructions for use of Omez contain information on contraindications for use. Capsules are not prescribed in the following cases:

  1. Individual intolerance to the main substance or auxiliary components.
  2. Severe renal or liver failure.
  3. Simultaneously with certain medications - digoxin, clopidogrel, ketoconazole, erlotinib, nelfinavir, atazanavir, tacrolimus.
  4. In children weighing less than 10 kg.

Important! It is necessary to warn your doctor about taking other medications to avoid negative consequences.

Release form of the drug omez

Omez is available in 20 mg capsules. active substance Omeprazole. Each box contains 10 or 30 capsules. The capsules are transparent, gelatinous, hard. The body of the drug is colorless, on both parts there is the inscription “OMEZ”. The capsule contains white or almost white granules.

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Omez 40 is a lyophilized powder for the preparation of a solution for infusion. 1 bottle contains 40 mg. active substance Omeprazole.

Omez for gastritis with high acidity

This medicine is perfect for eliminating the clinical symptoms of high acidity, as well as for normalizing this indicator of gastric juice.

An increase in pH is characteristic of gastroesophageal reflux, peptic ulcers, erosions, gastritis associated with Helicobacter pylori infection in the early stages.

Omeprazole or Omez belongs to the group of proton pump inhibitors (PPIs). This is a unique group because their mechanism of action is directly related to reducing the production of hydrochloric acid by blocking the proton pump involved in its production.

After the appearance of these drugs on the pharmaceutical market, the number of surgical operations involving vagotomy—cutting the branches of the vagus nerve innervating the stomach—dramatically decreased. This is how doctors treated high acidity and peptic ulcers before the advent of PPIs.

This medicine only works when the proton pump is functioning and HCL is being produced. And this process is active during the absorption of food. The process of producing hydrochloric acid is induced when a person eats something.

Therefore, the drug should be taken 30-40 minutes before meals to achieve the best therapeutic effect.

Brief information about Omeprazole

Omeprazole belongs to a group of drugs that reduce the production of hydrochloric acid, thereby lowering the acidity of gastric juice. This creates favorable conditions for the healing of damage to the gastric mucosa (ulcers, gastritis).

Omeprazole has practically no contraindications; it is not prescribed only if there is an intolerance to one of the components of the drug, pregnant and lactating women, as well as children under fourteen years of age.

The dosage of the drug is prescribed individually, depending on the disease and its severity. Omeprazole should be taken in the first half of the day, immediately before meals. The capsules are swallowed without chewing and washed down with a small amount of water.

How to take Omez correctly for gastritis

The course of treatment is prescribed by a gastroenterologist according to the protocol. Patients with high acidity can take capsules in the morning or at night. In most cases, it is recommended to take Omez for gastritis in an average therapeutic dose - 20 mg per day before or after meals.

In some patients, positive dynamics are observed when the amount of the substance is 2 times less than the standard one. If there is a severe course with pronounced clinical symptoms, then use the drug in a dosage of up to 40 mg per day. Take the medicine with clean water.

The doctor decides how many days to take a proton pump blocker depending on the type and severity of the pathology. The active substance is included in the eradication therapy regimen, which is used for 7-14 days. Taking Omez for gastritis complicated by a peptic ulcer lasts from 2 to 4 weeks. For reflux esophagitis in children and adults, the course of treatment is from 4 to 8 weeks.

The drug is allowed to be prescribed to children who have reached one year of age. However, the child's weight should be taken into account. Omez can be given to children weighing over 10 kg. Indications for treatment in the age group under 4 years are reflux esophagitis, symptomatic heartburn and acid regurgitation. In older people, peptic ulcer of the stomach and duodenum associated with Helicobacter pylori infection.

How to drink omez to prevent gastritis?

For preventive purposes, Omez can be used by people suffering from chronic gastritis. At the same time, the disease must be in remission - during an exacerbation, treatment and diet look completely different.

To prevent exacerbation of chronic gastritis, Omez can be taken before feasts, especially those accompanied by alcohol consumption. Here you can limit yourself to 10–20 mg of the drug once.

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It is extremely important to take the medicine simultaneously with a course of anti-inflammatory drugs (Ketanov, Diclofenac, Ibuprofen, etc.). These medications greatly disrupt the protective mechanisms of the gastric mucosa and, when taken in a course, often contribute to the development of gastritis and even gastric and duodenal ulcers. In such a situation, Omez is taken 20 mg 2 times a day throughout the entire period of taking anti-inflammatory drugs.

In addition, Omez should be used for preventive purposes in various diets, especially those aimed at reducing body weight. It is important that the diet is adequate - if you fast or significantly limit food intake, the drug will not be able to cope, and the weight will return soon after stopping the weight loss course.

What happens when you take the capsule

When taken on an empty stomach, the capsule dissolves, the contents are released and absorbed through the capillaries of the gastric mucosa. This process takes about half an hour.

When food then enters the stomach and HCl begins to be released reflexively, the drug blocks the H/K-ATPase or proton pump, causing hydrochloric acid production to be dramatically reduced. And also the symptoms of increased pH that bother patients disappear or decrease: heartburn, belching, epigastric discomfort.

Contraindications

The list of contraindications for taking Omeprazole is not too wide.

  1. It should not be taken by pregnant women or during lactation. In some cases, when a pregnant woman suffers from chronic gastritis, the doctor may take a risk and prescribe Omeprazole under constant supervision. Much more often, diet and gentler medications are used to treat gastritis in pregnant women.
  2. If, while taking Omeprazole, intolerance to one of the components of the drug is detected, treatment is interrupted and an analogue is prescribed.
  3. In the case of small patients under twelve years of age, the drug is usually not recommended. However, there are cases when taking Omepraol is justified (as a rule, these are severe esophagitis and peptic ulcers). In this case, the doctor must select a gentle dosage based on the child’s weight.
  4. If the patient has severe liver or kidney disease, they try not to prescribe the drug. The fact is that the medicine, in order to be eliminated from the body, is processed first by the liver and then by the kidneys. In the presence of serious diseases of the urinary system, the process of ridding the body of medicine is disrupted. This can trigger a variety of side effects and complications. If taking Omeprazole is still justified, patients with liver and kidney pathologies are prescribed the medicine in a gentle dosage.

Self-administration of the drug without carrying out all the necessary tests and examinations, as well as establishing a diagnosis, is strictly prohibited.

Uncontrolled use of Omeprazole, as a rule, does not help to cope with the real disease, but only adds to the patient’s health problems.

But the main danger of taking Omeprazole on your own is that by eliminating the symptoms, the clinical picture of the disease can be blurred. And this, in turn, can lead to untimely diagnosis of such serious diagnoses as gastric ulcers or malignant tumors.

Omez tablets for gastritis - instructions for use

This drug can be bought at any pharmacy without a prescription, but it is better if its use is justified and the prescriptions are made by the attending physician. After all, there are a great many reasons for inflammation of the digestive tract, and without proper examination, you should not use it.

The product may not have the desired effect, for example, if you take Omez for gastritis with low acidity. Or even lead to undesirable reactions of the body.

The doctor recommends this medicine if the patient, after examination, is diagnosed with the following pathological conditions:

  • stomach and duodenal ulcers, both in the acute period and in remission to prevent relapse
  • identified Helicobacter pylori infection. In this case, the drug Omez is used as part of a combined treatment regimen for gastritis
  • inflammatory lesions associated with gastrotoxic drugs, NSAIDs
  • reflux esophagitis, including to prevent the return of the disease after treatment
  • stress ulcers. May be recommended as prophylaxis in patients at high risk of developing them
  • Zollinger-Ellison syndrome

The medicine is available in the form of capsules of 20, 40 mg, powders of 20 mg for suspensions. 1 capsule contains the active ingredient omeprazole, as well as a number of excipients: mannitol, lactose, stabilizers, propylene glycol, CaCo3.

A lyophilisate is also available for the preparation of infusions administered intravenously in hospital settings.

The drug is not indicated for pregnant and lactating women.

The drug should not be recommended to infants and children of the first years of life if their weight is less than 10 kg.

It is strictly prohibited for use by persons with hypersensitivity to the active substance or to the auxiliary components of the drug.

You cannot take the medicine together with nelfinavir.

Usually well tolerated, but in rare cases side effects may occur:

  • decrease in the number of leukocytes, platelets. After stopping the medication, the blood count returns to normal.
  • allergic reactions in the form of urticaria, angioedema, and in case of intolerance - anaphylaxis
  • insomnia
  • headache, dizziness
  • dry mouth, stool disorder such as constipation or diarrhea
  • with long-term use there is a tendency to polyps of a benign nature in the gastrointestinal tract
  • dermatitis, urticaria

The duration of therapy and dosage, depending on the established disease, are prescribed by the doctor. It is usually recommended to take 20 mg/day (1 capsule) for 2-4 weeks, in some cases the dose may be doubled, and the course of treatment may be duplicated with a short break.

As part of combination therapy to get rid of Helicobacter, Omez is prescribed together with recommended antimicrobial drugs at least twice a day.

If you have problems swallowing, you can open the capsule and mix its contents with a small amount of non-carbonated liquid or fruit puree, and then allow the patient to swallow.

If you missed taking the medication, you must take the capsule without waiting until the next day.

Overdose is practically impossible, the medicine has low toxicity. Even with a daily intake of 12-13 capsules, no poisoning occurred.

In rare cases, overdose is possible in patients with severe liver and kidney failure. If, while taking the medication, this category of people experiences confusion, dry mouth, or headache, it should be discontinued.

For many patients suffering from heartburn, abdominal pain, belching and gastric discomfort, this medicine is a “lifeline”.

Many, after just a few days of taking it, note a significant improvement in their well-being. And after a course of treatment, inflammatory changes normalize or subside according to endoscopic examination.

Therefore, patients often abuse the medicine, drinking it for a longer period of time than was recommended by the doctor. Such lovers of self-medication should know how to drink Omez correctly for gastritis and remember some of the nuances that may arise in this case:

  • Long-term use of the drug helps reduce the absorption of vitamin B12. Its deficiency may be indicated by increasing pallor, increased fatigue, “snagging” in the corners of the mouth, burning sensation on the tongue, paresthesia and a feeling of pins and needles crawling along the limbs.
  • with long-term use, Mg deficiency may develop. If convulsions, interruptions in cardiac activity or arrhythmias occur while taking it, it is necessary to discontinue the drug and check the concentration of this trace element in the blood.

Monitoring Mg must be done before starting therapy when taking diuretics or digoxin together, and monitoring the electrolyte balance is also recommended during treatment.

Many women during pregnancy suffer from a physiological increase in acidity, especially in the last stages. After childbirth, existing problems with the gastrointestinal tract also worsen. Is Omez allowed for this category of people?

The instructions state that the effect of the drug on the course of normal pregnancy and fetal health has not been sufficiently studied. The substance also passes into breast milk and many clinicians believe that there is a potential risk for the baby.

During pregnancy and lactation, use is not indicated. If the patient is breastfeeding, but her condition requires treatment with this drug, lactation must be stopped while using the medicine.

Omeprazole for heartburn: how to take, mechanism of action, patient reviews

Omeprazole is a drug that inhibits the proton pump enzyme, which is prescribed for various diseases associated with excess hydrochloric acid in the gastric juice. It is also used in symptomatic treatment, so a gastroenterologist may recommend Omeprazole for heartburn.

Composition and dosage form

The drug is dispensed in the form of capsules containing 20 or 40 mg of the active ingredient - omeprazole. Contains anhydrous lactose and gelatin, starch and sucrose. One polymer blister contains ten gelatin capsules. The pack contains one or three blisters.

Mechanism of action for heartburn

Whether Omeprazole will help with heartburn depends on what triggered the symptom. By inhibiting H+-ATPase, omeprazole prevents the secretion of excess hydrochloric acid and thus reduces the acidity level of gastric contents.

If heartburn and sour belching are caused by increased acidity, Omeprazole will be effective. And although the drug is effective even against stimulated secretion, compliance with the diet will be necessary. Otherwise, the medicine will only temporarily eliminate the symptom, and with the immediate influence of an irritant - caffeine, nicotine, fatty foods - heartburn will return again.

In case of reflux esophagitis, the drug is associated with weakening of the signs of pathology and healing of the mucous membranes of the esophagus in more than 89% of cases. Omeprazole is also highly effective in the treatment of chronic and complicated forms of esophagitis, peptic ulcers, erosions, and gastritis. Has bactericidal activity against Helicobacter.

After oral administration, the drug is quickly absorbed, inhibits the secretion of hydrochloric acid for an hour and retains the effect until the end of the day. The ability to produce hydrochloric acid returns within a week after the end of the course of therapy.

When is the drug prescribed?

Omeprazole can be taken for heartburn - symptomatic treatment is indicated by the manufacturer in the instructions for the drug. Indications for use also include the following conditions and pathologies:

  • therapy and prevention of ulcerative-erosive lesions of the digestive tract;
  • prevention of exacerbations of gastric ulcers;
  • treatment of ulcers without malignancy;
  • eradication of Helicobacter - as part of complex therapy;
  • treatment of gastrointestinal pathologies associated with the use of non-hormonal painkillers;
  • reflux esophagitis;
  • pancreatic adenoma.

Children are recommended to use it for reflux esophagitis, heartburn, as well as for Helicobacter eradication under the supervision of a physician. Before giving capsules to a child, you should determine the cause of heartburn and consult a pediatrician and gastroenterologist.

Contraindications

The use of the drug is prohibited in case of high sensitivity to omeprazole or formative components. Use is also contraindicated if the patient has an allergy to substituted benzimidazoles. Should not be combined with atazanovir and nelfinavir. The doctor prescribing Omeprazole should be informed about all medications that are currently being taken.

Pregnancy and breastfeeding

There are no data on harm to a pregnant woman or fetus. The drug is approved for use during pregnancy if taken under the supervision of a physician. The active ingredient passes into breast milk, but the effect on the baby is unknown, therefore it is not recommended to use Omeprazole during breastfeeding.

Features of therapy

Treatment with Omeprazole may hide the manifestations of malignant ulcers and tumors in the stomach, thereby delaying diagnosis and treatment. If an ulcer is suspected or detected, it is recommended to exclude malignancy, especially if the following symptoms are present: causeless weight loss, periodic vomiting of blood, etc.

It is not recommended to combine Omeprazole with atazanavir. If this combination cannot be avoided, it is recommended to take them only under the supervision of a doctor and in strict dosage restrictions - the minimum therapeutic dosage of Omeprazole is prescribed.

Omeprazole may reduce the absorption of cyanocobalamin, which should be taken into account in patients with cachexia and vitamin deficiency. The drug can cause infections of the intestines and stomach, as it reduces the concentration of hydrochloric acid, which usually prevents the spread of infection. Due to the lactose and sucrose content, it is not recommended for patients with impaired absorption and processing of these substances.

Allowed for children over one year of age only according to a doctor’s indications and under his close supervision. Therapy directed against Helicobacter requires a combination with antibiotics on the recommendation of a doctor.

Analogues and cost

Analogues of the drug Omeprazole in action are:

  • Pariet;
  • Nexium;
  • Rabeprazole;
  • Omez;
  • Esomeprazole.

The price of a package of Omeprazole in Moscow pharmacies ranges from 54 to 128 rubles. The cost in pharmacies in other cities may differ; it is recommended to check it locally.

Patient reviews

“In my case, Omeprazole did an excellent job and replaced Rennie. The latter is more expensive, acts somewhat slower and the effect is shorter than that of Omeprazole. The latter is available in all pharmacies, is easy to find, acts quickly and, most importantly, for a long time. Acidity regulation is excellent, heartburn goes away very quickly.”

Ekaterina, Moscow

“My husband always gets heartburn and stomach pain due to stress; he always takes Omeprazole.

It helps quite quickly, although sometimes you have to take a course to restore the condition of your stomach. You should take it only as prescribed by your doctor - if you prescribe the dosage yourself, you may not be able to guess.”

Olga, Krasnodar

“Ever since my student years, gastritis reminds me of itself with constant heartburn and pain in the stomach. I take Omeprazole periodically - not with every heartburn, but when it appears frequently, I start taking it in a course. I haven’t tried anything more effective yet - it quickly eliminates heartburn, inflammation in the stomach decreases, and you can again forget about unpleasant symptoms for a long time.”

Lyudmila, Voronezh

Source: https://GastrituNet.online/lekarstva/ipn/ompr/omeprazol-ot-izzhogi.html

Treatment of gastritis with Omez and Denol

Often, when treating chronic gastritis, the doctor prescribes not one medicine, but several, with the goal of providing the most effective therapy and improving the patient’s condition.

But many patients mistakenly believe that if there are a lot of drugs (for example, when eradicating Helicobacter pylori infection, it is necessary to take three or four medications at once for 7-14 days), then they negatively affect the stomach and disrupt the treatment regimen. Take the pills separately, or drink only part of them.

https://www.youtube.com/watch?v=Wc2q3S36WWU

This cannot be done. Often, a doctor recommends taking both Omez and Denol at the same time. And this is completely justified.

The drugs have different compositions and different mechanisms of action. The bismuth-based product has an antibacterial, wound-healing and excellent anti-inflammatory effect, which, together with a proton pump inhibitor, work harmoniously to eliminate pathological processes in the stomach.

Treatment of gastritis with Omez and Denol at the same time gives good results, so you should not be afraid of a combination of two or more drugs for the stomach.

What you should not do is adjust the treatment regimen yourself, or swallow pills without prior examination. You should trust the experts in their field.

A study showed that drug treatment of gastroduodenitis against H. pilori in young adults reduced symptoms of dyspepsia. It is imperative to culture the crops for sensitivity to the drug, since resistance to metronidazole is growing. Antibiotics for gastroduodenitis are prescribed necessarily in case of pronounced changes in the mucous membrane and peptic ulcer during the period of remission.

The main drug from the group of proton pump inhibitors, which is prescribed for gastroduodenitis, is Omeprazole. The substance suppresses secretory function by 70-80% and, by changing the pH of the stomach, creates conditions for the death of the pathogen. Three treatment regimens for gastroduodenitis are used:

  1. 40 mg omeprazole, 500 mg clarithromycin twice daily, 1000 mg amoxicillin twice daily for 7 days;
  2. 20 mg omeprazole twice daily, 500 mg clarithromycin twice daily, 500 mg metronidazole twice daily for 7 days;
  3. 40 mg omeprazole, 500 mg metronidazole twice a day, 1000 mg amoxicillin (Amoxiclav) twice a day for 7 days.

The first treatment regimen leads to 98% effectiveness, the second eliminates the bacteria in 90%, and the third in 80% of cases. Proton pump inhibitors, such as Omez, Helol, should be taken for another two weeks after antibiotic therapy. These tablets for gastroduodenitis prevent metaplasia - changes in cells in the stomach and duodenum.

One-week therapy is supplemented with bismuth tripotassium dicitrate preparations. The drug De-Nol is prescribed to patients with resistance to antibiotics and previous unsuccessful attempts at treatment.

  • decreased stomach acidity;
  • restoration of motor skills;
  • improvement of mucosal function;
  • normalization of vegetative status;
  • treatment of concomitant pathologies.

For secondary gastroduodenitis and pathologies that began in childhood, treatment of all parts of the pathology is required - identifying the causes of inflammation.

Two types of drugs are used - antacids and antisecretory drugs. Depending on the concomitant pathologies, the gastroenterologist chooses which medications to take.

Antacids, such as phosphalugel, should be taken for heartburn immediately after meals or at night. They help in binding hydrochloric acid, therefore they restore the pH in the duodenum and relieve pyloric spasm.

  • an hour after eating during maximum production of hydrochloric acid;
  • an hour before meals - to restore acid-base balance due to gastric emptying;
  • with increased acidity at night to relieve pain.

The recommended medicine for gastroduodenitis to suppress acidity is H, K-ATPase blockers - Omeprazole, Emanera.

Nolpaza from this group of drugs reduces the risk of peptic ulcers when taking non-steroidal anti-inflammatory drugs and reduces heartburn.

Prokinetic drugs improve the interaction between the stomach and duodenum. Dopamine receptor antagonists block them, increasing gastrointestinal motility. They are used for gastroduodenitis, peptic ulcers, and biliary dyskinesia. One popular remedy is Motilium (domperidone).

The herbal preparation Iberogast is used in the treatment of functional dyspepsia, against spasms against the background of chronic gastroduodenitis. The product is suitable for children with colic. The herbs included in the composition reduce the hypersensitivity of stomach receptors, the production of hydrochloric acid and inflammation.

The drug Trimedat enhances the peristalsis of the digestive organs, improves the function of the esophageal sphincter, preventing heartburn and reflux. Emptying of the stomach is accelerated, so the mucous membrane is less injured. Antispasmodics Duspatalin and No-shpa relieve pain, but do not affect intestinal motility. They are prescribed to relieve spasms and colitis, which are possible during antibiotic therapy.

  • increased blood circulation in the mucous membrane;
  • suppression of proteolytic enzymes;
  • increased production of protective mucus.

The drug De-Nol additionally blocks the entry of Helicobacter into the cells of the mucous membrane and neutralizes the activity of bile. The gastroenterologist determines how many days to drink De-Nol depending on antibiotic therapy and the condition of the mucous membrane. The main purpose is an ulcer-like variant of gastroduodenitis and increased acid-forming function.

To enhance blood circulation in the mucous membrane, magnetotherapy with Almag-01 or Almag Plus, which are available for home use, is recommended. Less commonly, synthetic prostaglandins are used to protect the mucosa. Folic acid, vitamins A, E and group B have a protective effect.

Gastroduodenitis against the background of pancreatitis is associated with a lack of digestive enzymes. Therefore, when treating the underlying disease, Festal is prescribed to relieve the digestive tract. Acute epigastric pain is also associated with exocrine pancreatic insufficiency, which is corrected with Creon.

Gastroduodenitis with low acidity develops due to atrophy of the mucosa or reflux of bile from the duodenum. In case of low acidity, detected using pH-metry, the drug Hilak-Forte is prescribed. At an acidic pH, lactobacilli increase damage to mucous membranes. Therefore, dyspeptic symptoms associated with dysbacteriosis and flatulence cannot be treated independently without examination by a specialist.

Gastroduodenitis against the background of infectious liver lesions, Giardia and Ascaris causes insufficient synthesis of peptide hormones. Biliary dyskinesia is diagnosed due to dysregulation of the gallbladder muscles. The doctor recommends taking a herbal remedy with artichoke extract - Chofitol, along with therapy against gastroduodenitis. To support liver function, herbal remedies such as Tykveol are chosen.

What can replace Omeprazole in the treatment of gastritis?

Orthanol - can be a replacement for the drug Omeprazole.

In case of individual intolerance to the drug, it can be replaced with an analogue recommended by the doctor. Omeprazole analogues also reduce the acidity of gastric juice and help relieve inflammation of the gastric mucosa.

  • Omez. A drug based on omeprazole, often prescribed for inflammatory diseases of the stomach and duodenum. This is an Indian-made drug; it is available not only in tablets, but also in injections. Side effects include nausea, abdominal pain, constipation or diarrhea, arrhythmia, allergic reaction, and drowsiness.
  • Orthanol. This drug also contains omeprazole and has a relatively low price, but differs in that the maximum concentration of the drug is reached over a longer period of time.
  • Rabelok. The drug is based on rabeprazole, available in the form of tablets and solution for injection. Not recommended during pregnancy, breastfeeding, or individual intolerance to the drug.
  • Ontime. The drug contains rabeprazole, but of all analogues it has the lowest ability to penetrate tissue (bioavailability). Recommended for hyperacid gastritis, gastric ulcers and erosion, GERD, as well as in combination with other drugs for the eradication of Helicobacter pylori. The drug is not used in pediatric practice and is extremely rarely prescribed to children.
  • Hasek. A drug based on omeprazole. The maximum effect is observed on the fourth day after starting treatment. Available in capsule form for oral administration. The drug Gasec-10 is taken 1-2 capsules per day. The drug is not recommended for people with fructose intolerance.

All of the drugs listed contain either omeprazole or rabeprazole. In case of severe side effects while taking omeprazole, they are replaced with more gentle drugs that envelop and protect the walls of the stomach: Reni, Gastal, Almagel, Maalox.

Detailed information about the treatment of gastritis is in the thematic video:

Read along with this article:

  • Omeprazole - method of using tablets
  • Omez - main analogues, drug substitutes and their differences
  • Omez in capsules and tablets: instructions for use
  • Almagel for gastritis: when and how to take
  • How to take De Nol: action and indications for use
  • Tablets for gastritis and ulcers. How to make sense of an extensive list?
  • Ranitidine, features of the drug use
  • No need to endure: painkillers for the stomach
  • Tablets for gastritis: antacids, proton pump inhibitors,…

Side effect of the drug

Before treating gastroduodenitis in adults, you need to understand what medications they are currently taking. Panangin, as a seemingly safe combination of potassium and magnesium, can cause a burning sensation in the stomach - an exacerbation of gastroduodenitis.

Taking aspirin and non-steroidal anti-inflammatory drugs leads to type C gastritis caused by chemical exposure. The probiotic Vetom 3, advertised online, can cause exacerbation of chronic infections, bloating and diarrhea.

Antibiotic treatment suppresses beneficial intestinal microflora. The main side effects are diarrhea, abdominal pain and nausea. Your doctor may prescribe probiotics. Linex, Bifidumbacterin eliminate dysbacteriosis associated with massive exposure to drugs.

The drug De-Nol, prescribed for heartburn, is well tolerated, sometimes causing an accumulation of bismuth, a change in the color of the stool and tongue.

The weakened condition of the patient before and during treatment indicates atrophic gastritis or low acidity. In this case, anemia develops due to B12 deficiency.

Pallor, weight loss, lack of appetite are indications for endoscopic examination before prescribing antibiotics or other drugs. Ulcerative conditions are the most common exacerbations of gastroduodenitis, which must be taken into account when choosing a treatment regimen.

https://www.youtube.com/watch?v=X-OFARB4XB4

Patients in most cases report good tolerability of the drug. If the average therapeutic dosage of Omez is prescribed for gastritis or other pathological conditions, practically no adverse symptoms are observed. However, some patients, especially with long courses of treatment, may experience adverse reactions, which are presented in the table.

Organs and systemsClinical signs
Blood
lymphatic
Thrombocytopenia, leukopenia, agranulocytosis, pancytopenia
ImmuneHypersensitivity reaction, angioedema, anaphylactic reaction or shock
DigestiveVomiting, nausea, bowel dysfunction - diarrhea or constipation, abdominal pain, bloating, dry mouth, dysbacteriosis
MetabolismDecreased levels of magnesium, sodium, calcium
Nervous,
psycho-emotional status
Headache, taste disturbance, drowsiness, hyperarousal, insomnia, aggression, depression, hallucinations, impaired consciousness, ringing in the ears, increased sweating
Organs of visionFuzzy perception
RespiratoryBronchospasm
Liver,
bile ducts
Increased levels of enzymes in the blood, jaundice, liver failure, encephalopathy in patients with existing pathology
Skin and subcutaneous
fat
Itching, rash, urticaria, dermatitis, alopecia, photosensitivity, erythema multiforme, toxic epidermal necrolysis
Musculoskeletal
system
Myalgia, arthralgia, muscle weakness
Kidneys,
urinary tract
Interstitial nephritis
GenitalsGynecomastia

Carefully! To date, the effect of omeprazole on sexual development and growth characteristics in children with long-term use has been little studied.

Contraindications and side effects

Omeprazole should not be taken by pregnant women.

Side effects are rare when taking Omeprazole. In some cases, diarrhea, dry mouth, increased thirst, headache, and fatigue occur.

An allergic reaction can manifest itself in the form of a rash, itching, hives, and swelling. If such side effects are observed, the drug will have to be stopped.

There are practically no side effects if the dosage and doctor’s recommendations are followed. If unpleasant symptoms appear, you must stop taking the drug or reduce the dosage; the side effects will quickly disappear (within two weeks without additional treatment). Omeprazole, like any drug, has its contraindications.

  • Pregnancy and lactation. For pregnant women with chronic gastritis, taking Omeprazole is a relative contraindication. In rare cases, under the supervision of a doctor, it is allowed to take the drug, but more often only a gentle diet and safer drugs are prescribed, for example, Almagagel.
  • Individual intolerance. If individual intolerance to Omeprozole is observed, it is replaced with an analogue drug.
  • Children's age up to 12 years. Children's age is considered a contraindication, but in rare cases, with severe esophagitis and peptic ulcer in a child, Omeprazole is prescribed to children over one year of age. The dosage is determined taking into account the child’s weight: 10-20 mg 1-2 times a day.
  • Severe liver and kidney diseases. The drug is destroyed in the liver and excreted by the kidneys in the urine. With serious pathologies of these organs, the removal of Omeprazole from the body becomes difficult, which leads to various side effects and complications. If necessary, patients with renal and liver failure are prescribed Omerazole in a reduced dosage.
  • Under no circumstances should you take the drug without examination and diagnosis by a doctor. Drinking Omeprazole for any abdominal pain is dangerous, since even when relief occurs, the clinical picture is blurred. As a result, you may miss a serious illness, such as a stomach ulcer or malignant tumor.

Read: Mezim - composition and indications for use of the drug

Which is better: Omez or Omeprazole for gastritis

The drug is a generic drug for the treatment of gastritis and other pathologies of the digestive tract. The proton pump inhibitor is developed taking into account all quality requirements. Unlike the original medicine, during production it is possible to add other excipients, which can slightly reduce the time of accumulation of the main compound in the body.

Analogs

The treatment regimen for gastric inflammation allows the use of other drugs with a similar mechanism of action. For gastritis, you can replace Omez with analogues, which are presented in the table.

TitlesDosage forms
Nolpaza (pantoprazole)Tablets 20 and 40 mg
OmeprazoleCapsules 20 and 40 mg, solution for infusion 40 mg
EsomeprazoleSolution for infusion 40 mg
Lansoprol (lansoprazole)Capsules 15 and 30 mg
RabeprazoleTablets 20 mg

Omez's analogs

Like all other drugs, Omez has a number of analogues, which differ in the same composition and effect as the original medication. Products can differ only in the amount of active substance per dose, additional components and release form. So, if there are side effects from taking Omez as prescribed by a doctor, it can be replaced with the following medications:

  • Omeprazole is a cheaper and completely similar drug produced in Russia;
  • Famotidine;
  • Alumag;
  • Pariet;
  • Novobismol;
  • De-nol;
  • Phosphalugel;
  • Omegast.

This list can be continued for a long time, because today pharmaceutical companies produce a large number of drugs that restore the functioning of the stomach. This is due to the high relevance and high incidence of gastric diseases in the country.

Important information: How to earn and identify gastritis at home

Composition and mechanism of operation

Omeprazole helps reduce the secretion of gastric juice and is suitable for the treatment of gastritis with high acidity. Its activation occurs only in the stomach environment, and therefore it does not affect other organs. You can take Omeprazole for atrophic gastritis with preserved or increased acidity, as it also has an antibacterial effect, participating in the fight against Helicobacter pylori. It potentiates the effect of antibiotics and improves the condition of patients, reducing the severity of pain.

Omeprazole tablets have an enveloping effect on the mucous membrane. They create favorable conditions for the healing of ulcers and erosions on the walls of the organ. The tablet contains 10, 20 or 40 mg of the active substance. It also contains a number of auxiliary agents, such as glycerin, gelatin, nipazole, titanium dioxide and others.

In addition, this medicine has the following positive effects:


This medication will help reduce the feeling of heartburn.

  • reduces pain, especially on an empty stomach;
  • eliminates spasms;
  • normalizes stool, reducing the severity of diarrhea and constipation;
  • reduces heartburn;
  • stops nausea and belching of sour contents.

Omeprazole is a proton pump inhibitor and acts on the parietal cells of the stomach. It suppresses the secretion of not only hydrochloric acid, but also pepsin. It is also capable of providing a gastroprotective effect without affecting the functional activity of Castle factor. The onset of action of the drug occurs approximately an hour after use. The maximum effect is achieved after 2 hours. The drug can have a therapeutic effect throughout the day.

Omeprazole description of the drug

Externally, Omeprazole looks like a crystalline white powder. According to its chemical structure, it belongs to benzimidazole derivatives. It has a weak alkaline reaction, dissolves well in alcohols and very poorly in water. Omeprazole is a prodrug. This means that the substance contained in it does not have healing properties in itself, but acquires these properties after entering the internal environment of the body.

Dosage forms of Omeprazole - tablets, capsules, powder for the preparation of solution for intravenous administration. Capsules can have a dosage of 10 and 20 mg, tablets - 10, 20 and 40 mg. The powder comes in 40 mg bottles.

The effect of the drug occurs quite quickly - within 1 hour and lasts about 23 hours. Omeprazole 20 mg reduces the pH level in the stomach to a value of 3 and maintains it at this level for approximately 17 hours. During the course of treatment at a dose of 20 mg daily, the maximum effect is achieved on days 3-4. After the course, the effect lasts for several more days. The medicine can be prescribed to adults and children starting from 5 years of age. Elderly patients can take omeprazole without dose adjustment.

It is recommended to take Omeprazole before or during meals, preferably in the morning. Take the medicine with a small amount of water. When using Omeprazole in capsule form, they should not be chewed. The usual dosage is 20 mg per day for 1 dose. However, in some cases, for example, with resistance to antiulcer drugs, it can increase to 40 mg.

The duration of treatment and method of application depend on the disease. For peptic ulcers, the course of treatment usually lasts 4 weeks, for gastritis and heartburn - 2 weeks. It is not recommended to use the drug for more than 2 months. With a long course of treatment, a break of several months should be taken. When prescribing Omeprazole, the instructions for use can be adjusted by the doctor depending on the circumstances.

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