The drug "Nolpaza" is a drug from the group of inhibitors; this medication reduces the production of hydrochloric acid, thereby reducing the acidity of gastric juice. “Nolpaza” is used to treat various diseases of the esophagus and stomach, in which it is necessary to reduce acidity. Thus, this medicine is used for peptic ulcers, erosive gastritis, stomach pathologies caused by the use of Aspirin, Indomethacin, Ibuprofen, and the like. It is also used for stress ulcers, as well as in the case of the development of gastroesophageal reflux disease. Next, we will look at the instructions for using Nolpaza, find out what analogues are available, and also learn about its interaction with alcohol.
Compound
1 tablet of the gastroresistant drug
Pantoprazole sodium sesquihydrate (in terms of pantoprazole) – 20 mg;
Excipients, including sorbitol.
1 tablet of the gastro-resistant drug Nolpaza 40 contains: Pantoprazole sodium sesquihydrate (in terms of pantoprazole) – 40 mg; Excipients, including sorbitol.
The active ingredient is the substance Pantoprazole, which is included in the tablets in quantities from 20 to 40 mg.
In the powder used for injections, its proportion is 40 mg.
Nolpaza contains additional ingredients:
- Sorbitol.
- Calcium stearate.
- Mannitol.
- Sodium carbonate.
Elena Malysheva about parasites in the human body
“I have been appearing on your TV screens for many years and we have repeatedly touched upon the problem of various diseases of our body. They often talked about serious and not so serious illnesses, as well as about various methods of cure. Today we will talk about secretive but very terrible pests with which we have been living for years, without even knowing where all our ailments and diseases come from - these are Parasites.”
Read more{amp}gt;{amp}gt;{amp}gt;
Contraindications
Gastric ulcer is not the only area of application of this drug. It is prescribed for various pathological processes of the stomach and esophagus.
Tablet forms and powder in injection form have the same effect.
Their appointment occurs in the following cases:
- Diseases of the esophagus (gastroesophageal reflux disease, esophagitis, esophagospasm), which are characterized by the reverse reflux of food from the stomach into the esophagus.
- When the functions of the digestive system are disrupted, which causes:
- Belching acid.
- Heartburn that does not respond to conventional antacid medications.
- Spasmodic pain in the epigastric region.
- Increased gas formation, often accompanied by abdominal asymmetry and flatulence.
- Pathological processes that resulted in peptic ulcer disease, or for prophylactic purposes to prevent relapses.
- A combination together with antibacterial therapy, the purpose of which is to destroy the bacterial flora of Helicobacter pylori.
- Diseases that result in a significant increase in the concentration and production of gastric juice (Zollinger-Ellison disease).
- In the treatment of chronic pathological diseases of the musculoskeletal system, anti-inflammatory non-steroidal medications are used. When prescribed, the causes of the inflammatory process are eliminated, but their tablet forms lead to the appearance of ulcers and erosions on the gastric mucosa. To prevent the development of such side effects, Nolpaza is used. While protecting the gastric mucosa, it does not reduce the effect of antibacterial drugs
Absolute
In this case, Nolpaza is not taken or prescribed.
The following pathological conditions can be included in this group:
- The occurrence of an allergy to the ingredients of Pantoprazole sodium, or individual intolerance.
- Teenagers who have not yet turned 18 years of age. Research has not yet been carried out on this age category.
- If the dosage exceeds 40 mg, and the patient has severe liver or kidney disease, then prescribing the drug may cause side effects.
- For disorders that are caused by a violation of the psycho-emotional state (depression of various etiologies).
Relative
This remedy is not recommended for use in patients with such pathologies (but with extreme caution, under the supervision of medical staff, this remedy is sometimes prescribed in a hospital setting).
List of pathologies:
- Extensive focal lesions of the gastric mucosa, in the treatment of which non-steroidal anti-inflammatory drugs are prescribed for a long time.
- Gastric bleeding, which is a consequence of the development of ulcers and erosions.
- They try not to prescribe this dosage form to elderly people.
- In the event that vitamin B12 hypovitaminosis is treated in parallel with Cyanocobalamin, and it does not give positive dynamics.
For the treatment of patients suffering from mild gastroesophageal reflux disease, as well as for the treatment and prevention of patients with reflux esophagitis of varying severity.
For the treatment of patients suffering from peptic ulcers of the stomach and duodenum, Zollinger-Ellison syndrome and other conditions accompanied by hypersecretion.
For the prevention of ulcerative lesions of the mucous membrane of the stomach and duodenum in patients who have been receiving non-steroidal anti-inflammatory drugs for a long time.
The drug can be prescribed in combination with antimicrobial drugs in Helicobacter pylori eradication regimens.
Increased individual sensitivity to the components of the drug, including hereditary fructose intolerance.
The drug is not used to treat children and adolescents under the age of 18 due to the lack of reliable data on the safety and effectiveness of pantoprazole in this age category.
The drug in the form of tablets containing 40 mg of the active ingredient is not used in combination with antimicrobial drugs for the treatment of patients suffering from severe renal and/or liver dysfunction.
The drug is not intended for the treatment of patients with neurotic dyspepsia.
The drug should be prescribed with caution to patients suffering from liver disease; with long-term use of the drug in such patients, the level of liver enzymes should be monitored. The drug should be prescribed with caution for the prevention of ulcerative lesions of the gastric and duodenal mucosa in patients who are prescribed long-term use of non-steroidal anti-inflammatory drugs, and There are also other risk factors for developing ulcers or gastrointestinal bleeding.
In particular, for prevention, the drug is prescribed with caution to patients with a history of gastric or duodenal ulcers, gastrointestinal bleeding, as well as elderly patients. Caution should be observed when prescribing the drug to patients at risk of developing hypovitaminosis B12.
Reviews
Most of the reviews about Nolpaz are positive. This is primarily due to the high effectiveness of the drug in the treatment of various stomach diseases. People write that this drug is good at eliminating the symptoms of gastritis and gastric dyspepsia. Thus, this medicine relieves people from heartburn, sour belching, pain and a feeling of heaviness that arise against the background of chronic pathologies. Also, in case of errors in nutrition or any stress, Nolpaza copes well with unpleasant symptoms.
Reviews very often indicate that Nolpaza quickly and at the same time effectively relieves any pain in the stomach area, relieving heartburn and curing exacerbation of gastritis, peptic ulcers or GERD.
As for the negative reviews about this drug, we can say that they are few in number and are due to the lack of a therapeutic effect in specific cases. There are also comments that Nolpaza can cause side effects that are difficult to tolerate, as a result of which a person is forced to stop treatment with the drug. Thus, the effect of Nolpaza is not suitable for everyone, and therefore the advisability of its use must be decided with a doctor.
Release form
- Nolpaza tablets 20-40 mg, in foreign currency, 14 pills, in cardboard packaging, 28 pieces. An annotation is also included.
- Nolpaza powder for injection, sold in ampoules of 40 mg. Cardboard packages contain one bottle. To use it, the contents are dissolved with saline solution.
Interview of the Ministry of Health with Dr. Ivashkin
“The pancreas with pancreatitis can be restored in a simple way! Or you can lose it forever...”
Read more{amp}gt;{amp}gt;{amp}gt;
Gastro-resistant (enteric-soluble) tablets, 14 pieces in a blister pack, 1, 2 or 4 blister packs in a cardboard box.
Mode of application
The drug is intended for oral use. It is recommended to swallow the tablet whole, without chewing or crushing, with a sufficient amount of liquid. It is recommended to take the drug before meals. If the drug is prescribed once a day, the tablet should be taken in the morning.
The duration of the course of treatment and the dose of the drug are determined by the attending physician individually for each patient.
Adults suffering from a mild form of gastroesophageal reflux disease are usually prescribed 20 mg of the drug once a day. The duration of the course of treatment is usually 14-28 days; if necessary, the course of treatment can be extended to 2 months.
For treatment and prevention of exacerbation of reflux esophagitis, adults are usually prescribed 20 mg of the drug once a day. If there is an increased risk of relapse of the disease, the dose is increased to 40 mg of the drug once a day. After the patient’s condition improves or the risk of relapse decreases, they switch to taking the drug at a dose of 20 mg 1 time per day.
Adults receiving therapy with non-steroidal anti-inflammatory drugs are usually prescribed 20 mg of the drug once a day to prevent ulcerative lesions of the mucous membranes of the stomach and duodenum.
Patients with peptic ulcers of the stomach and duodenum are usually prescribed 40 mg of the drug once a day. When using the drug in Helicobacter pylori eradication regimens, 40 mg of pantoprazole is usually prescribed 2 times a day in combination with antimicrobial drugs. Nolpaza is recommended to be taken morning and evening.
Patients suffering from Zollinger-Ellison syndrome, as well as other diseases that are accompanied by hypersecretion, are usually prescribed the drug at an initial dose of 40 mg 2 times a day. If necessary, the dose is gradually increased to 80 mg of the drug 2 times a day. When prescribing the drug to patients suffering from impaired liver function, it should be taken into account that the maximum daily dose of the drug for patients in this category is 20 mg of pantoprazole.
For patients suffering from impaired renal function, as well as for patients over 65 years of age, the drug is prescribed in normal doses. When using the drug for a long time, it is recommended to monitor liver function. When using the drug for more than 1 year, the patient's condition should be monitored. Before starting to use the drug Nolpaza, a malignant tumor of the esophagus and stomach should be excluded.
pharmachologic effect
The main indication for which this drug is prescribed is hypoacid activity, the ability to reduce the enzymatic function of the stomach.
When prescribing the drug Nolpaza, its antibacterial effect on the pathogenic microflora of the stomach is taken into account. In the case of combined treatment with antibacterial drugs, its antimicrobial quality may increase.
This allows it to be used if the patient has stomach damage from Helicobacter pylori bacteria.
When the drug Nolpaza enters the human body, its effect begins after 60 minutes, gradually accumulating, reaching its peak after 3 hours. After stopping treatment, the remnants of this compound are eliminated over four days, mainly through the intestines.
Pharmacodynamics and pharmacokinetics
When Nolpaza tablets enter the stomach, they dissolve and block the synthesis of hydrochloric acid. As a result of this action, the level of basal secretion of hydrochloric acid in the human body decreases. After consumption, the maximum effect is achieved within two hours. The potent substance does not slow down the motility of the gastrointestinal tract.
After completion of treatment and administration of the drug, secretory activity is restored after 4 days. During the period of therapy, the level of serum gastrin concentration in the body increases because the production of hydrochloric acid decreases. High chromogranin content can lead to a deterioration in diagnostic accuracy, which is aimed at identifying neuroendocrine tumors.
When a lyophilisate is introduced into a patient’s body, most of the hydrochloric acid is blocked. The patient's basal and stimulated acid secretion decreases . The main substance has a high level of chemical stability. There is no information in medical practice that Nolpaza can reduce the effect of other drugs.
Pantoprazole is eliminated from the gastrointestinal tract within a short period of time. The maximum level of concentration is observed 2 hours after application. The biological availability of the drug is 80%. You can take the tablets regardless of meals. Most of the metabolites are excreted by the kidneys. Patients diagnosed with chronic renal failure can take the full dosage of the drug.
When lyophilisate is administered intravenously, metabolic processes occur in the liver. Most of the drug is excreted by the kidneys, the remaining metabolites penetrate into the intestines. Patients should not adjust the dosage on their own.
Side effects
The drug of this pharmacological group is well tolerated by patients, but sometimes, if used and prescribed incorrectly, undesirable reactions may occur that appear in different systems of the body.
Let's take a closer look:
- The hematopoietic system may respond with the appearance of thrombocytopenia or leukopenia.
- In the digestive system, disruptions may occur that lead to severe damage to the liver tissue and are accompanied by obstructive jaundice and cholestasis. Dryness of the mucous membranes of the oral cavity, nausea and vomiting, excessive gas formation (flatulence), stool upset (diarrhea or constipation), and periodic pain in the abdominal area may also occur.
- With large doses of this medication, arthralgia and myalgia may develop in the bones and muscles.
- Very rarely, on the part of the central nervous system, patients who are prescribed Nolpaza experience a disorder of the psychoemotional state; it is accompanied by insomnia at night, drowsiness during the day, the appearance of migraines, and blurred vision.
- Allergic reactions often occur; they are accompanied by skin itching and rashes. In severe conditions, erythema multiforme, Lyell's syndrome and Quincke's edema may develop.
- Milder side effects include weakness, loss of strength, hyperthermia, chest pain, and swelling. Biochemical blood tests may show an increase in cholesterol and triglyceride levels.
From the gastrointestinal tract and liver: gastralgia, stool disorders, nausea, flatulence, increased levels of liver enzymes.
In isolated cases, the development of hepatotoxic effects of the drug, the development of jaundice, including that accompanied by liver failure, was noted.
From the central nervous system: headache, dizziness, visual disturbances, emotional lability. From the urinary system: edema, interstitial nephritis. Allergic reactions: skin rash, itching, urticaria, erythema multiforme, photosensitivity, Stevens-Johnson syndrome, Lyell's syndrome. In isolated cases, the development of Quincke's edema was noted. Others: muscle pain, increased body temperature, hypertriglyceridemia.
Therapeutic effect
The main area of application and purpose of Nolpaza is the treatment of stomach ulcers that arise for various reasons. Also, due to its ability to reduce acidity, it is often prescribed for the treatment of gastritis and esophagitis, reflux esophagitis.
Due to the fact that the production of hydrochloric acid decreases, the gastric mucosa begins to heal, and the ulcers heal:
- Nolpaza’s ability to suppress an acidic environment activates the effect of antibiotics on the bacteria Helicobacter pylori. This leads to their complete neutralization.
- When treatment of pathological conditions occurs, as a result of which gastric juice is refluxed into the esophagus (reflux gastritis, esophagitis), the therapeutic effect is observed after 10 days of using this medication.
- Nolpaza significantly increases gastrin levels and normalizes its concentration in the bloodstream. This effect gradually decreases after discontinuation of the drug and returns to normal levels.
Interview with a proctologist
“I have been treating hemorrhoids for 15 years. According to statistics from the Ministry of Health, hemorrhoids can degenerate into a cancerous tumor within 2-4 years after the onset of the disease.
The main mistake is delaying! The sooner you start treating hemorrhoids, the better. There is a remedy that the Ministry of Health officially recommends.”
Read more{amp}gt;{amp}gt;{amp}gt;
General information about the drug
The presented drug is produced in Slovenia. It is produced by a pharmaceutical concern called KRKA. The developers provided two types of this medicine, namely: Nolpaza tablets and a solution for injection are produced. The biconvex tablets are oval in shape and coated with an easily dissolving brown coating. The storage temperature of this drug should not exceed twenty-five degrees. As for the shelf life of this medication, it is five years.
View gallery
Many people are interested in whether Nolpaza and alcohol are compatible? We'll talk about this below.
This drug is classified as an anti-ulcer drug. The active component of the drug suppresses the function of the proton pump in the cells of the stomach. As a result, the production of hydrochloric acid stops. The drug is taken regardless of the etiology of the stimulus. The indications for Nolpaza are indicated in the instructions.
Patients who are forced to take any other medications at the same time must inform their doctor about them, the fact is that the drug slows down the absorption of medications, depending on the level of acidity in the stomach.
Pregnancy
At the moment, there is not enough experience with the use of the drug in women during pregnancy and lactation.
When conducting laboratory studies on rats, data were obtained that when taking the drug at a dose of more than 5 mg/kg body weight, some embryotoxic effect of pantoprazole develops. The drug can be prescribed during pregnancy by the attending physician, who must carefully weigh the expected benefits for the mother and the potential risks for the fetus.
During pregnancy, the drug should be prescribed in minimal effective doses and for a short period.
There are no data on the excretion of the drug in breast milk. If it is necessary to use the drug during lactation, you should consult with your doctor and decide on the possible interruption of breastfeeding.
Instructions for use
The first thing you need to do when prescribing Nolpaza is to undergo an ultrasound examination and fluoroscopy. This will eliminate malignant neoplasms in the digestive system of the patient’s body. Since subsequent administration of Nolpaza can smooth out the clinical manifestations of these diseases.
Instructions for use:
- Nolpaza can be used through intravenous injections or droppers.
The use, dosage and duration of the course of therapy with Nolpaza is prescribed only by a doctor. It is based on the study of anamnesis, instrumental and laboratory studies. Basically, the dosage depends on the general condition, age and the presence of hepatic or renal pathology. - If tablet forms of Nolpaza are prescribed in a single dose, then it is best to take them on an empty stomach before breakfast 15 or 20 minutes. In the case of a double dose, the second pill is taken before dinner.
- If Nolpaza is used for prophylactic purposes, preventing a recurrent form of peptic ulcer, Nolpaza is prescribed in a single dose of 20 mg in the morning.
- In severe pathological processes, the dose is doubled and its volume is 40 mg. Nolpaza is recommended for use in the morning and evening hours.
- If the patient experiences nausea, cramping pain in the lower abdomen, or upset stool, then changes in the prescription of the drug must be made and taken once in the amount of one tablet.
- In case of heartburn, which is accompanied by acid belching, this remedy is consumed in the amount of 1 tablet (20 mg). If such a dosage does not lead to an improvement in the patient’s condition, it is increased to 40 mg, divided into 2 doses per day. Subsequent appointments of therapy will depend on the level of gastric juice production, and the treatment period may be extended.
- When treated with non-steroidal, anti-inflammatory drugs, Nolpaza should be used throughout the entire course of NSAID treatment. A daily dose is prescribed from 2 to 4 pills. On average, such therapy lasts no more than 8 weeks.
- To neutralize the activity of the Helicobacter pylori bacterium, it is necessary to undergo a course of treatment lasting up to 2 weeks, with the daily dose divided into two doses, and its volume can reach up to 80 mg per day.
- If the patient has liver pathologies, then treatment is prescribed with constant monitoring of laboratory tests of liver enzymatic parameters.
- Nolpaza is not prescribed to elderly people. Only in rare cases is a dose prescribed that does not exceed 40 mg over 24 hours.
Nolpaza can be used through intravenous injections or intravenous drips. To make an intravenous injection, the contents of the bottle must be diluted with ten milliliters of saline solution (0.9% sodium chloride).
To set up a dropper, the contents of the bottle are dissolved in 100 ml of sodium chloride (0.9%) or glucose (0.5%) in the same volume. The dripping rate should not exceed 80 drops per minute. The ready-made solution for injections and droppers is used immediately; a delay is allowed for no more than 12 hours.
The tablets and infusion solution have the same indications:
- Tablet forms of Nolpaza are best taken on an empty stomach 15-20 minutes before breakfast.
Parenteral administration of Nolpaza is used in more severe cases of treatment of pathological processes. Intravenous vision can also be prescribed in cases where oral administration is not possible. The duration of intravenous injections can last for a week. - This therapy is prescribed for the treatment of Zollinger-Ellison syndrome. The recommended daily dose for this pathology does not exceed 80 mg.
- For the treatment of reflux esophagitis, esophagospasm, parenteral administration is also acceptable. Prescribed 40 mg (one bottle) once a day.
Pregnancy
The effect of Nolpaza on the body of a pregnant woman has not yet been sufficiently studied. In any case, the prescription of Nolpaza must be agreed with the attending physician. Only he can assess the risk of using this drug and carefully weigh its benefits for the female body.
If a prescription does occur, then this drug is taken in minimal doses, with a short course of treatment.
During lactation, there is no data on the effect on the health of the newborn. Therefore, if therapy with Nolpaza occurs, it is better to stop breastfeeding.
Childhood
Due to the fact that clinical trials have not been conducted in children under 18 years of age, Nolpaza is not prescribed.
Are you afraid of ulcers? Take Nolpaza!
And this is not an exaggeration. After all, heartburn is a harbinger of a disease such as reflux esophagitis, and from it it’s a stone’s throw to an ulcer. Nolpaza is a medicine that belongs to the proton pump inhibitors. What does this mean? This drug reduces the formation of hydrochloric acid, which reduces the acidity of gastric juice. Therefore, the medication is used in the treatment of such dangerous ailments as gastritis, ulcers, gastroesophageal reflux, and stomach pathologies caused by taking certain pharmaceutical drugs (Aspirin, Ibuprofen, Indomethacin, Nise).
Nolpaza is produced in the form of yellow-brown tablets (they are taken orally) and lysophylate, which is used to prepare an injectable composition. The drug in tablets is sometimes called simply “Nolpaza 40” or “Nolpaza 20 mg”. The instructions for use explain that exactly this amount of the main active ingredient (Pantoprazole) will be contained in one pill. In addition, it contains hypromellose, titanium dioxide, macrogol 6000, mannitol, water, propylene glycol and other substances. The tablets have an oval configuration and are produced in packages containing from 14 to 28 pieces.
Interaction with other drugs
Nolpaza may reduce the effectiveness of the following drugs:
- A group of drugs whose absorption directly depends on the degree of stomach acidity. These include antifungal dosage forms (Ketoconazole, Itraconazole).
- Pharmacological group that is prescribed for the treatment of HIV-infected patients.
- Coumarin anticoagulants (Phenprocoumon or Warfarin).
Some drugs, on the contrary, become more active when Nolpaza is prescribed:
- Patients undergoing treatment for cancer with Methotrexate should stop using this drug during treatment with Nolpaza. Due to the fact that it is capable of increasing its concentration in the bloodstream.
- When using antibacterial therapy, Nolpaza potentiates the effect of antibacterial agents.
This medicine does not have a significant effect when taken:
- Diclofenac and Dicloberla.
- Digoxin.
- Caffeine.
- Infinom.
- Piroxicam.
- Theophylline.
- Oral contraception.
Parallel use of Pantoprazole and antacids is allowed. It is also possible to prescribe it together with antibiotics.
When used in combination, the drug reduces the bioavailability of ketoconazole and other drugs that are characterized by pH-dependent absorption.
Despite the fact that the studies did not reveal a clinically significant interaction of the drug with drugs whose metabolism occurs with the participation of the cytochrome P450 system, such interactions cannot be excluded, since the cytochrome P450 system is involved in the metabolism of pantoprazole.
When the drug is used in combination with coumarin anticoagulants, the effectiveness of the latter may change, therefore, if it is necessary to use these drugs simultaneously, it is recommended to monitor the prothrombin time.
When pantoprazole was used in combination with antacid drugs, no changes in the pharmacokinetics of these drugs were observed.
special instructions
Before starting treatment with Nolpaza, the presence of malignant neoplasms should be excluded, since drug therapy can mask symptoms and delay the correct diagnosis of the disease.
If after four weeks of therapy with Nolpaza the desired therapeutic effect is absent, then additional examination is necessary.
Pantoprazole may reduce the absorption of vitamin B12 in achlorine and hypohydria.
Long-term treatment with Nolpaza requires constant monitoring of the patient.
Vehicle management
If the patient’s work involves increased concentration and is accompanied by the need to quickly respond to current situations, then in these cases everything depends on the individual tolerance of Nolpaza.
Sometimes it can cause sudden dizziness; when such a symptom appears, it is best to refrain from such work, take a sick leave, and undergo the full course of treatment prescribed by the doctor.
Interview with Gennady Malakhov about wax-cream Zdorov
“...I want to touch on one of the important topics of intimate illness. We will talk about hemorrhoids and their treatment at home...”
Read more{amp}gt;{amp}gt;{amp}gt;
Recommendations for use of the drug
Nolpaza is prescribed, regardless of the release form, only to adult patients. Intravenous administration is used for hospital treatment. Nolpaza tablets are successfully used at home. The drug is taken orally unchanged before meals with a small amount of water. The specialist will select the dose for each patient individually. It is necessary to warn your doctor about the simultaneous use of Nolpaza and any of the following medications:
- antiviral drugs for the treatment of immunodeficiency (for example, Ritonavir);
- antitumor drug Methotrexate;
- blood thinner Warfarin;
Warfarin is used to treat heart and vascular diseases - antibiotic Rifampicin.
In addition, dose adjustment may be required in case of severe liver diseases, in which the organ does not cope well with its responsibilities for neutralizing and eliminating drugs.
Overdose
At this time, there have been no reports of overdose. When pantoprazole is administered parenterally (intravenously) at a dose of 240 mg over 2 minutes, the drug is well tolerated by patients.
In the event of the development of undesirable effects when using excessive doses of the drug, gastric lavage, administration of enterosorbents and symptomatic therapy are indicated.
This negative consequence occurs extremely rarely when treating various pathological conditions with this drug. It can occur if the prescribed dose of the drug is not followed (most often, this happens with parenteral administration).
In this case, a clinical picture of poisoning develops. It is accompanied by the appearance of severe headache, increased heart rate, nausea or vomiting, increased sweating, and pale skin.
If after these procedures there is no improvement in the condition, you must contact a clinic or sanitary inspection station. In particularly serious cases, you need to call a doctor at home, he will make prescriptions that will eliminate the symptoms of poisoning.
Alcohol compatibility
The annotation that comes with Nolpaza does not contain any information about interaction with alcoholic beverages. However, this does not mean that drinking alcoholic beverages is acceptable.
When using them, the following undesirable consequences can be noted:
- There is a decrease in the level of therapeutic effects of Nolpaza; ultimately, its effect may be reduced to zero effect.
- Alcoholic drinks lead to irritation of the gastric mucosa, and, as a result, increase its secretory function.
- If the patient’s main diagnosis is a peptic ulcer, then the alcohol he drinks does not allow the ulcers to scar.
- Can alcoholic drinks provoke the development of side effects that will serve as a criterion for discontinuing Nolpaza?
You can drink alcohol only if you have completed the full course of therapy and at least 4 days have passed after it (this is the withdrawal period for Nolpaza),
Price
This medicine can be purchased at pharmacy chains or in online stores. To avoid purchasing counterfeits, it is best to contact pharmacies.
Average price in Russia:
- Nolpaza tablets 20 mg in an amount of 28 pieces has an average price of 190 rubles. When purchasing the same number of tablets, but with a dosage of 40 mg, its average price is 300 rubles.
- The drug in powder form for parenteral administration is sold for 140 rubles. For one bottle.
"Nolpaza" for gastritis
A remedy is prescribed for gastritis when this disease occurs against a background of excessive acidity. The drug corrects the synthesis of hydrochloric acid, eliminating the pronounced symptoms of this pathology. Nolpaza is quite well absorbed and easily tolerated by the body; it can demonstrate a long-lasting therapeutic effect, but only if the medicine is taken correctly. This remedy has contraindications and side effects, therefore, before taking the medicine, it is important to consult a gastroenterologist.
How long to take Nolpaza?
The duration of treatment for gastritis and stomach ulcers is from 4 to 8 weeks. In order to prevent such conditions, Nolpaza is prescribed for use in an amount of 20 mg per day. Treatment of peptic ulcer. When eradicating Helicobacter pylori bacteria, the course of using Nolpaza is at least 7 days. For Zollinger-Ellison syndrome, the duration of therapy is individual.
