Duspatalin indications for use and contraindications analogues

Published 04/03/2020 · Comments: · Reading time: 8 min · Views: Post Views: 441

Irritable bowel syndrome is a fairly common disease today. It is characterized by functional disorders in the form of painful sensations in the abdomen (spasms, seething, bloating) and stool disorders in the direction of diarrhea, constipation, or their alternation. There is a change in stool consistency at normal frequency. For symptomatic treatment of these problems, doctors use a complex of drugs, which includes myotropic antispasmodics. Duspatalin is one of the regularly prescribed drugs.

Composition of Duspatalin for constipation, for intestines, for bloating

We will tell you below whether Duspatalin helps with constipation.

According to the instructions, the mentioned medication is available in the form of opaque and hard gelatin capsules. They have a prolonged action, and also have size No. 1, white color and the marking “245” on the body. White or almost white granules are used as the contents of the capsules.

What does the drug “Duspatalin” contain (not everyone knows what this medicine helps with)? Its main ingredient is mebeverine hydrochloride. In addition, the drug contains auxiliary elements such as ipromellose, magnesium stearate, methacrylic acid, methyl methacrylate, ethyl acrylate copolymer, talc and triacetin.

As for the capsule shell, it consists of gelatin and titanium dioxide.

This drug can also be purchased in the form of tablets with the same active ingredient.

These white, film-coated tablets have the international name Mebeverine (named after the main active ingredient).

Sold without a doctor's prescription. But you should carefully study the instructions and apply them strictly according to the recommendations.

Each of us has experienced an upset stomach at least once in our lives. In medicine, this condition is called “dyspepsia”. The phenomenon is not pleasant and is accompanied by nausea and diarrhea. In order for this condition to go away as quickly as possible, it is important to know which remedies to use for indigestion.

Symptoms

Dyspepsia is easy to recognize by its striking symptoms, which often appear after the patient has had a heavy lunch or dinner (at this time the stomach begins to actively work). The main symptoms of indigestion include:

• pain attacks in the upper abdomen;
• bloating;
• attacks of nausea;
• unpleasant heartburn;
• belching (in this case, air itself or food particles may escape);
• gagging;
• feeling of fullness in the stomach.

Causes

This medication has no serious contraindications. It should not be used only in the following conditions:

• during pregnancy (due to insufficient data on safety and effectiveness);
• in minors (due to insufficient data on safety and effectiveness);
• hypersensitivity (personal) to any ingredient of the medicine.

This medication is taken orally. Extended-release capsules should be swallowed whole. In this case, they must be washed down with a sufficient amount of liquid (at least 100 ml).

The capsules in question must not be chewed. This is due to the fact that their shell promotes prolonged release of the drug.

This drug is prescribed in an amount of 200 mg twice a day. It is advisable to take the medication 20 minutes before meals (in the morning and before bed).

The duration of use of this medication is not limited.

Experts have conducted studies to study the interaction of this drug only when combined with alcohol. They demonstrated a complete absence of any negative effect.

The drug "Duspatalin" can be replaced with such drugs as "Niaspam", "Papaverine", "Sparex", "Trigan", "Trimedat", "Spascuprel", "Dicetel", "Buscopan", "Bendazol", "Dibazol", "No-shpa."

Most reviews about this medicine are positive. Patients report that this drug is very effective. It helps eliminate not only functional disorders of the gastrointestinal tract, but also get rid of various diseases.

There are a large number of medications for constipation. Duspatalin is a modern myotropic antispasmodic, which is a very popular remedy for the treatment of intestinal spasms and relaxation of the intestinal muscles. In addition, the drug effectively eliminates pain in the gastrointestinal tract and treats gallbladder dysfunction.

Description

The popularity of this remedy has been made possible by the absence of side effects and low toxicity, as a result of which the use of Duspatalin for constipation has practically no contraindications. The main effect of the drug is the effect of Mebeverine hydrochloride on the intestinal muscles, which relieves spasms.

As a rule, the medicine is supplied to pharmacies in the form of tablets or capsules with granular contents. The protective shell consists of titanium dioxide and gelatin, which allows the capsules to dissolve only in the intestinal environment. Capsules are distributed into dies in blister packaging and sold in the same form in the pharmacy.

According to reviews regarding the problem of whether Duspatalin helps with constipation, most of them are positive. Moreover, there is a lot of evidence that the chemical composition of this remedy works well not only for constipation.

Relieving spasms allows you to cure abdominal cramps, colic in the gastrointestinal tract, as well as eliminate excessive gas formation and flatulence. Irritable bowel syndrome and other digestive disorders usually require the use of Duspatalin or other effective antispasmodics.

Duspatalin capsules are most preferable for use

The use of medications must be prescribed by the attending physician. As a rule, the drug in the prescribed dosage is taken three times a day some time before meals. This is necessary because the main symptoms that the antispasmodic fights appear soon after eating.

Despite the fact that the drug is practically non-toxic and does not accumulate in the body, the attending physician gradually reduces the dosage as the patient’s condition changes. The first signs of significant improvement during the therapeutic course usually appear already in the second or third week of daily use of Duspatalin.

The use of Duspatalin for constipation and bloating is not the only possible option for using an antispasmodic drug. Duspatalin is usually used when almost any muscle spasms occur in the gastrointestinal tract.

The main indications for use of the drug are irritable bowel syndrome and spasms. However, during pregnancy and lactation, it is not recommended to use Duspatalin in the presence of milder, albeit less effective, agents. In general, the main contraindications for use include the following:

• pregnancy, when the first negative symptoms appear;
• patient age under 10 years;
• individual intolerance to specific components in the drug;
• some congenital blood diseases, as well as kidney and liver diseases.

The drug is available by prescription and if there are still capsules left after the end of the therapeutic course, they should be used only with the permission of the attending physician, and if the risk of spasms returning is high.

Duspatalin also comes in tablets, but these are less popular than capsules

The use of Duspatalin, even due to its low toxicity, can still cause some allergic reactions in the form of rashes and itching on the skin, slight swelling on the face and quickly passing dizziness.

However, the drug is good because it does not block acetylcholine receptors, which allows you to avoid increased heart rate, visual and hearing disturbances, dry mouth and partial disorientation.

Application

In the case of tablets, the drug should be taken half an hour before meals, swallowing the medicine whole and without chewing, washing it down with a glass of clean water. In most cases, the dosage recommended by the doctor is 1 tablet per dose, 3 times a day.

Gradually, as the indicators improve, the doctor will recommend reducing the dosage, taking in some cases not a whole tablet, but half of it, and subsequently reducing the medication to two or one tablet per day in the first half of the day.

Such a dosage regimen can be adjusted according to the individual physiological characteristics of the patient and the clinical course of the disease. Every week during treatment, the doctor assesses the patient’s condition and, if necessary, changes the prescribed dosages or leaves them at the same level.

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When painful symptoms disappear, the dosage of the medication can be gradually reduced and the patient's health condition can be closely monitored. Abrupt cessation of drug use is not recommended, as this may cause withdrawal syndrome and deterioration of the general condition of the body.

It is recommended to take Duspatalin with a glass of water when consuming

At the same time, the question arises, does Duspatalin itself cause constipation? As a rule, no. However, excessive use of the drug can lead to an overdose, which will lead to negative neurological symptoms, including, in addition to increased excitability, dizziness and headaches, the development of constipation.

Excess medication can be removed from the gastrointestinal tract by rinsing and using activated carbon, which adsorbs drug residues and allows them to be quickly removed from the digestive tract.

In children

As a rule, the use of Duspatalin is permissible only from the age of 10 years. However, some doctors insist on a lower limit of 12 years. In any case, if there are analogues that are acceptable for use by adolescents, it is better to use them than Duspatalin.

However, the effectiveness of Duspatalin makes its use attractive. As a rule, the symptoms and indications for use of the drug in children and adolescents are the same as in adults. Spasms and colic in this case are often not only a consequence of eating low-quality food, but also the result of psychological stress.

Reviews

Patients who received Duspatalin leave more positive reviews about it. They indicate that the drug allows you to quickly cope with intestinal and stomach colic, eliminate functional digestive disorders, and abdominal pain after overeating.

Patients with irritable bowel syndrome note that Duspatalin makes it possible to get rid of pain, regulate bowel movements, and reduce bloating. Patients receiving antibacterial treatment often suffer from dysbiosis, which causes severe abdominal pain. Duspatalin copes well with this problem. The pain begins to subside within half an hour after the first dose of the drug. Moreover, the capsules have a prolonged action.

Duspatalin has positive reviews from patients suffering from inflammation of the pancreas and gallbladder. The drug quickly relieves spasm, which leads to normalization of the patient's condition. Even with exacerbation of pancreatitis and cholecystitis, pain can be completely managed within 2-3 days. Patients with chronic pathologies take Duspatalin for preventive purposes and note its high effectiveness in preventing the development of relapses.

Negative reviews about Duspatalin are extremely rare. They boil down to the fact that the drug did not eliminate pain during exacerbation of inflammation of the pancreas or gall bladder. However, you should not expect a lightning-fast solution to the problem, since pain relief should take 2-3 days, not several hours. Therefore, such reviews can be considered not entirely justified.

Some people become disillusioned with the drug and take it inappropriately. Patients often indicate that Duspatalin did not help cope with gastritis or stomach ulcers. But this medicine is not intended to treat these diseases. Duspatalin is an antispasmodic and its main effect is to reduce pain.

Reviews from experts

Practicing gynecologists note that Duspatalin allows you to get rid of intestinal colic in pregnant women, regardless of the nature of their occurrence.

Therapists and gastroenterologists indicate that Duspatalin can be successfully used in the treatment of irritable bowel syndrome, pancreatitis, cholecystitis, as well as to get rid of negative symptoms that arise from functional digestive disorders.

Doctors indicate that Duspatalin cannot be used as a monocomponent for pancreatitis. The drug should be part of a complex therapy regimen. Otherwise, it will not be possible to achieve recovery.

How to use the drug

1 tablet three times a day 20 minutes before meals.

Duration - 2 weeks.

Avoid overdose. In this case, there may be changes in the nervous and cardiovascular systems.

There is no need to take any action.

• rash, itching of the skin;
• swelling up to Quincke's edema;
• labored breathing;
• cardiopalmus;
• increased blood pressure and sweating.

With caution in cases where:

• there are signs of anemia;
• symptoms appeared for the first time;
• there is bleeding from the anus or blood is present in the stool;
• you have recently been treated with antibiotics;
• age over 50 years

In these cases, prior consultation with a doctor is required.

To determine whether Duspatalin helps with bloating, you need to study the indications of this drug.

How you take Duspatalin depends on a number of factors, including:

• patient's age and body weight;
• drug tolerance.

In the case of tablets, they must be used following the instructions below. Take Duspatalin tablets 30 minutes before meals. The tablet is swallowed whole (it must not be chewed or bitten) and washed down with at least half a glass of boiled water.

Reception regimen: 3 times a day. The duration of the course depends solely on the clinical effect, until spastic pain ceases to torment the patient.

It is important to remember that the withdrawal of Duspatalin does not occur immediately after achieving the effect (this can greatly harm the body and cause the development of withdrawal syndrome). Instead, the withdrawal period is extended over 3-4 weeks, following the following regimen:

• first week - half an hour before breakfast and lunch, take one whole tablet, and half before dinner;
• second week - half an hour before breakfast and dinner, take one whole tablet;
• third week - take one whole tablet in the morning, and half in the evening;
• fourth week – one whole tablet is taken in the morning.

This scheme is unified and, accordingly, works for most patients. But the period of “refusal” also depends on the individual characteristics of the human body.

For example, if the patient shows a normal condition when discontinuing the drug, the dosage can be reduced even by a whole tablet. In the opposite situation, either the withdrawal period increases, or each dosage reduction is half a tablet.

For capsules, a slightly different application procedure is provided. Due to the higher concentration of the active ingredient, taking Duspatalin in capsules is limited to two per day - 20 minutes before breakfast and dinner.

For adults

Adult patients can use the drug in accordance with the above standards. But given the high effectiveness of the antispasmodic, it should be taken only in accordance with medical prescriptions.

For children

Duspatalin is not prescribed for children under 12 years of age. For them, it is replaced by drugs that are “milder” in their effects.

For adolescents over the age of 12 years, Duspatalin can already be prescribed if they experience spasms and pain in the gastrointestinal tract (often caused by regular consumption of low-quality food - primarily fast food).

Now it is worth considering two main contraindications for most medications - periods of pregnancy and lactation.

Antispasmodics are often used by women during pregnancy. The reason is that the smooth muscles of the uterus are prone to spasms, which are transmitted to the organs of the gastrointestinal tract. To relieve spasmodic pain in the gastrointestinal tract, Duspatalin is used, since it selectively affects the tone of the smooth muscles of the digestive organs, without affecting the blood vessels and the uterus.

For these reasons, Duspatalin is often used in the treatment of spastic conditions of the digestive organs in pregnant women. But it is still not recommended to start using the drug without consulting a doctor.

The same is true for nursing mothers during lactation. They can also take the drug, but under the supervision of a doctor, since the effect of Duspatalin on breast milk has not been fully studied.

1 tablet three times a day 20 minutes before meals.

Avoid overdose. In this case, there may be changes in the nervous and cardiovascular systems.

There is no need to take any action.

How to take Duspatalin for constipation

Due to the fact that this antispasmodic only affects increased peristalsis without suppressing normal functioning, it is safe. But this does not mean that it can be abused and taken for the slightest problems with the intestines.

The duration of Duspatalin therapy is determined depending on the severity of the pathology and the neglect of the underlying disease. You can take the drug for up to four weeks, but only under the supervision of a doctor. The tablets should be swallowed whole with plenty of water.

Duspatalin dosage according to instructions:

• first week - 1 tablet in the morning and lunchtime, half in the evening;
• second week - 1 tablet. in the morning and in the evening;
• third - 1 tablet in the morning and half a tablet. In the evening;
• fourth - one tablet in the morning.

The treatment regimen can be changed by the doctor; it is often selected individually for each patient. Duspatalin should be taken before meals, and if side effects occur or if you feel worse, stop treatment and consult a specialist.

Indications and contraindications

Of course, such an antispasmodic as Duspatalin cannot have any contraindications. With regard to pregnant women and nursing mothers, it has already been said above - for them, use can be carried out with caution and under the supervision of a doctor.

Duspatalin is contraindicated in the following cases:

• in case of hypersensitivity and allergic reactions to the components of the drug;
• when taking medications containing alcohol (incompatible with alcohol).

If the patient has bloating and gas, and Duspatalin is contraindicated, it should be replaced with other tablets aimed at eliminating these problems, listed in this article.

Recommended as symptomatic treatment:

• painful symptoms;
• spasms in the intestinal area;
• any other unpleasant signs caused by irritable bowel symptoms;
• sensations of bloating, flatulence;
• disturbances in the consistency and shape of stool;
• diarrhea or constipation, their alternation.

Indicated for internal use, after administration it is quickly and 100% absorbed.

The main active ingredient is mebeverine:

• coordinates the work of the smooth muscles of the intestines, without excessive relaxation, this helps to quickly relieve spasms;
• in 4 weeks completely restores healthy intestinal motility;
• eliminates stool disorders;
• Forms healthy consistency and color of stool.

Quickly eliminates:

• rumbling in the stomach, seething;
• feeling of heaviness, fullness;
• cramping pain.

Prescribed by gastroenterologists as an independent treatment for IBS or as part of general therapy for the disease.

It is one of the most powerful, but completely safe drugs. Particular attention should be paid to tablets for those who:

• often gets nervous and gets into stressful situations;
• becomes overtired, emotionally or physically;
• abuses snacks on the go;
• eats enough at night;
• suffered intestinal infections and did not fully recover.

The tablets are completely metabolized in the body, the remains are quickly eliminated from the body by the kidneys.

The drug does not have a negative effect on the fertility of men or women. Does not affect the ability to drive a car or operate complex machinery.

Registration number: LP 001454-24052017. It has a trade and international name. Included in the international register. Possesses valid quality certificates and licenses. Permitted for sale in our country.

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The antispasmodic drug contains:

• mebeverine hydrochloride;
• lactose;
• potato starch;
• povidone and talc;
• Magnesium stearate.

The tablets are round in shape, coated with talc, gelatin, sucrose, and acacia gum.

Packaged in blisters of 10, 15 or 20 pieces. The package may contain a different number of such blisters, from 1.5 to 6.

1 piece three times a day 20 minutes before meals. Swallow without chewing and wash down with plain water.

The duration of treatment is not limited. No cases of overdose have been identified.

Pregnancy, breastfeeding, lactose intolerance, other components of the composition, age under 18 years.

Skin allergies - hives, skin rashes, weakness, decreased blood pressure, increased sweating.

Is not allowed.

Not available for under 18s.

Validity period is 5 years from the date of issue. After expiration, dispose of it. Store at a temperature no higher than 30 degrees, keep away from children.

It turns out that irritable bowel syndrome is one of the most common diseases around the world. For me it manifested itself as pain in the abdomen and discomfort after every meal. The gastroenterologist prescribed this particular remedy. I took it patiently for 2 whole months, but significant improvements occurred. The price, of course, is steep, but the efficiency is worth it.

Catherine

I took it after surgery on the intestines, and there were residual effects in the form of cramping pain and spasms. Helped me. I bought 30 pieces, it was enough for 15 days, that was enough.

During the treatment of a stomach ulcer, due to the use of numerous drugs, intestinal function went wrong and motility was impaired. It helped me personally, without any side effects or contraindications. Although they exist, you need to read the instructions carefully.

Michael

Both my mother and I took this remedy. The feedback is only positive. I bought several packages and drank them, following the instructions. Gradually, bowel function became normal, no more unpleasant symptoms.

Sold in any pharmacy chain, as well as in an online pharmacy. Choose the one with lower prices or discounts.

Duspatalin not only helps with pain, but is also effective in treating concomitant reflex disorders such as nausea, vomiting, diarrhea and constipation, and bloating. By tidying up the functioning of the intestinal muscles, it simultaneously relieves these unpleasant symptoms.

The annotation to the drug contains a list of pathologies for which Duspatalin helps:

1. abdominal cramps accompanied by combat syndrome;
2. intestinal and biliary colic;
3. dyskinesia of the gallbladder and ducts;
4. irritable bowel syndrome;
5. acute cholecystitis;
6. condition after removal of the gallbladder with stones;
7. secondary spastic conditions due to impaired outflow of hepatic secretions.

Duspatalin is contraindicated in pregnant women and patients allergic to mebeverine.

When using the medication, undesirable reactions are possible:

• allergic manifestations, mainly on the skin - urticaria, exanthema, Quincke's edema;
• anaphylactic shock (with hypersensitivity).

Such adverse reactions have been identified in post-marketing practice, so the frequency of their occurrence has not been precisely established.

Duspatalin is contraindicated in children under 12 years of age. During periods of gestation and lactation, the medication is prescribed with caution due to the characteristics of the physiological state of women and only in capsulated form. A teratogenic effect from taking mebeverine has not been identified; the active substance of the drug and accompanying substances in the composition do not have a negative effect on the fetus. During periods of lactation and breastfeeding, mebeverine does not pass into breast milk in doses that are significant for the baby.

It must be remembered that this drug belongs to the same group of myotropic antispasmodics as drotaverine (No-shpa, Papaverine), often used during the gestational period to reduce the tone of the smooth muscles of the uterus, and it is impossible to combine antispasmodic drugs due to the risk of overdose .

Other contraindications include increased individual sensitivity to the components of the drug. Since Duspatalin is incompatible with alcohol, it is necessary to consult a specialist when taking medications containing alcohol and their combination.

Duspatalin is classified as a drug with a low likelihood of side effects, but in some cases the following symptoms may occur:

• dizziness;
• digestive disorders such as nausea, difficulty defecating or loose stools;
• headache;
• skin manifestations: itching, rash, urticaria, exanthema, etc. with hypersensitivity to the components of the drug;
• local swelling.

Since it is known that the drug Duspatalin in rare cases can cause dizziness as a side effect of taking it, it is recommended that at the initial stage of therapy, when assessing the effect of the drug on the body and possible manifestations of side effects, to refrain from driving and work associated with increased concentration, reaction speed or requiring maintaining body balance in difficult conditions.

No-shpa

Another good and effective substitute for Duspatalin, which is popular among both doctors and patients. The main purpose of No-shpa is to relieve pain and muscle spasms of various origins. This can be either the digestive or genitourinary system.

The drug contains only one active ingredient, namely drotaverine. Available in both tablets and solutions for injection.

It is recommended to take it to relieve muscle tone in the stomach, intestines, gallbladder, kidneys, uterus, and blood vessels. Can be taken during pregnancy to relieve increased muscle tone and prevent premature birth.

However, there are some contraindications, namely: patients under 6 years of age, breastfeeding period, pathologies of the liver, kidneys or heart, the presence of an allergic reaction to one of the components of the drug.

Very rarely, for example, in case of overdose, negative symptoms such as insomnia, migraine, tachycardia, decreased blood pressure, and diarrhea may occur.

Customer reviews about the drug Duspatalin for gastrointestinal problems

It will take only 14 days to get rid of the symptoms of irritable intestines, improve its functioning, and get rid of the causes of discomfort.

It has a complex, targeted effect, does not disrupt the functioning of other organs and systems, is absolutely safe, has a minimum of contraindications and side effects.

I learned about it from my doctor and bought it if necessary. The stool was restored immediately, and other symptoms of irritable bowel went away.

I really like its soft and comfortable action. It helps quickly, I didn’t find any side effects.

I like the result. I took it for 2 weeks and got rid of diarrhea of ​​unknown origin.

I always have it in my first aid kit. I accept it myself and give it to my family. An excellent remedy for unpleasant abdominal symptoms.

The intestine is the most important organ of the human body, responsible for the state of immunity. You should support its work and take care of it by eating right, avoiding stress and bad habits.

But if it has already failed, then Duspatalin will come to the rescue.

These white, film-coated tablets have the international name Mebeverine (named after the main active ingredient).

Sold without a doctor's prescription. But you should carefully study the instructions and apply them strictly according to the recommendations.

The maximum course is 14 days. If after this period there is no improvement, you should consult a doctor.

Basic actions:

• has antispasmodic and analgesic properties;
• restores intestinal motility;
• heals its smooth muscles;
• used when feeling discomfort in the abdomen and stomach;
• restores healthy microflora;
• fights pathogenic microorganisms;
• normalizes stool, eliminates constipation or diarrhea, restores consistency, color, frequency of trips to the toilet;
• relieves cramps, bloating, flatulence, and other symptoms.

Helps regardless of what causes problems in the gastrointestinal tract:

• poor nutrition, lack of dietary fiber, nutrients;
• bad habits, including smoking and alcohol abuse;
• sedentary lifestyle, lack of sports in life;
• daily stress;
• chronic fatigue - both mental and physical.

Decomposition products are excreted naturally in the urine within a short time.

It is not recommended to use during pregnancy and breastfeeding; it is better to replace it with another, safer one based on natural ingredients. There were no results confirming its safety during this period.

Duspatalin - side effects

According to patient reviews and doctors' observations, the medicine is often well tolerated and does not cause negative reactions in the body. On the contrary, many note its high effectiveness and safety, including due to the drug’s ability to quickly exhibit therapeutic activity while maintaining normal intestinal motility.

Even with an increase in the dose of Duspatalin, adverse reactions occur with minimal probability, and these include:

• allergic manifestations (urticaria, Quincke's edema);
• headache;
• dizziness;
• nausea.

With an overdose of mebeverine, there are cases of development of hyperexcitability of the central nervous system. It is worth noting that due to the existing risk of developing side effects during treatment with this drug, it becomes necessary to abandon activities that require increased concentration and speed of psychomotor reactions (for example, driving a car). You also need to keep in mind that when taking alcohol together, the effectiveness of the medicine is significantly reduced.

Contraindications to taking Duspatalin, side effects of the drug

Duspatalin is a latest generation antispasmodic that is effective for spasms and pain in the intestines. It is non-toxic and has virtually no side effects. Due to its wide spectrum of action, Duspatalin is popular among many patients. This medicine can often be found in Russian home medicine cabinets.

The medicine should be taken half an hour before meals, swallowed whole and washed down with a glass of water. The standard dosage is one capsule three times a day. The duration of treatment depends on the onset of clinical effect - the course is not limited by other factors. Long-term use is possible until the pain goes away.

• 1 week - in the evening the dose is reduced by half a tablet;
• Week 2 - limited to 2 tablets per day;
• Week 3 - drink only half the tablet in the evening;
• Week 4 - leave a single dose of 1 tablet.

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There are drug substitutes that are used for irritation of the gastrointestinal tract. These include Trimedat, No-shpa, Drotaverine, Mebeverine, Dicetel, Sparex, Odeston. Many of them have a different active ingredient that has a similar therapeutic effect, that is, they relieve spasms and pain. It is worth noting that Duspatalin analogues are cheaper than the original.

Duspatalin for constipation has good reviews; only those patients who did not adhere to the instructions during treatment or carried out therapy without preliminary diagnosis speak negatively about it. It is necessary to understand that the drug does not help against all types of intestinal congestion. Therefore, self-medication may not only be useless, but also aggravate the problem even more.

This drug belongs to the group of myotropic antispasmodics of the latest generation. Its main effect in case of constipation is aimed at relaxing the intestinal muscles and relieving spasms. Therefore, Duspatalin helps with constipation caused by the following pathologies:

• spasms of the gastrointestinal tract;
• removal of the gallbladder;
• biliary colic;
• cholecystitis;
• pancreatitis;
• organic spasms;
• flatulence and dysbacteriosis;
• chronic colitis.

The advantage of Duspatalin is that it does not suppress the natural work of peristalsis, but acts exclusively on increased motor skills. Therefore, the product is excellent for normalizing the contraction of peristalsis and smooth muscles of the colon.

Duspatalin is aimed at relaxing spasmodic areas of smooth muscles, reducing the increased tone of smooth muscles of the digestive system, which determines its use for the following diseases and manifestations of dysfunction:

• spasms and pain caused by them in the abdominal cavity;
• intestinal colic of various etiologies;
• irritable bowel syndrome (as an auxiliary symptomatic remedy in complex therapy);
• biliary colic and functional disorders of the gallbladder, in which hypertonicity of the sphincter of Oddi is noted;
• maintaining the functionality of the gastrointestinal tract after cholecystectomy;
• secondary spastic conditions of the digestive tract, arising under the influence of diseases and pathologies of the gastrointestinal tract (cholecystitis, pancreatitis, etc.);
• functional digestive disorders with pain symptoms, etc.

Pharmacokinetics of Duspatalin: the drug is absorbed through the walls of the small intestine into the bloodstream, after which it is converted into metabolites in the liver and excreted from the body mainly in the urine. The rate of absorption and excretion depends on the rate of release of the active substance, determined by the form of the drug - tableted or encapsulated with a prolonged release of Duspatalin components.

Doctors are not inclined to regard constipation as an independent disease and consider this ailment to be a characteristic symptom of impaired intestinal functionality. And to get rid of the symptom of the disease, it is necessary to treat it. That is why the drugs prescribed by gastroenterologists for constipation: Trimedat or Duspatalin are considered the most popular.

Duspatalin is a medicine from the group of myotropic antispasmodics. The activity of the drug is due to the action of mebeverine, which is included in its composition.

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The therapeutic potential of mebeverine allows the drug to be used in the treatment of many intestinal pathologies associated with disruption of its functioning. And although Duspatalin is not a laxative, its use for constipation helps normalize stool.

Thanks to the properties of mebeverine, the following therapeutic effect is achieved:

• dilation of blood vessels in intestinal tissues;
• relaxation of muscles, the increased activity of which has led to spasms;
• maintaining a normal level of peristalsis;
• pain relief;
• elimination of symptoms that can irritate the intestines - nausea, constipation, flatulence, bloating.

Taking Duspatalin does not affect the movement of feces, but affects the intestinal muscle fibers. By restoring the natural functionality of muscles, Duspatalin helps normalize motility and natural bowel movement for constipation and bloating.

Duspatalin is presented in two pharmaceutical forms - tablets 125 mg and capsules, the content of mebeverine is increased to 200 mg. The medicine is approved for use from 12 years of age.

Most often, gastroenterologists prescribe Duspatalin as part of the complex treatment of spastic disorders. The development of spasms is characteristic of chronic diseases of the gastrointestinal tract and disorders of the digestive processes.

It is not recommended to treat constipation with Duspatalin on your own. It should be remembered that this drug is not a laxative and therefore can only help if there are indications specified in the instructions:

• abdominal pain;
• functional pathologies of the gastrointestinal tract and biliary tract;
• hypermotor dyskinesia of the gallbladder;
• complications of peptic ulcer;
• irritable bowel syndrome;
• exacerbation of cholelithiasis.

In addition, Duspatalin for constipation is prescribed for all types of intestinal disorders that provoke constipation, including dysbiosis.

The standard treatment regimen for constipation with Duspatalin involves taking it three times a day - one tablet half an hour before meals, since eating can affect the absorption of the drug and reduce the therapeutic effect. After taking the tablet, it is recommended to take it with water.

If taking Duspatalin three times a day for a week brings improvement in well-being, doctors prescribe reducing the daily dose to two doses per day, one tablet. It is possible that reducing the dosage will cause symptoms to return. In such cases, it is necessary to return to the previous course of treatment.

The total duration of therapy can be four weeks, subject to full control of the situation by the attending physician.

For most patients, Duspatalin helps with constipation without causing adverse reactions. However, violating the dosage or self-treatment without the help of a doctor can cause complications.

The appearance of a side effect is indicated by a deterioration in well-being after taking Duspatalin:

• pain in the back of the head;
• feeling of discomfort in the stomach;
• weakness, trembling in the limbs;
• rash or red spots on the skin;
• dizziness;
• loss of appetite.

Such manifestations indicate individual sensitivity to the drug. If you notice any discomfort, you should consult a doctor to replace Duspatalin with an analogue.

Treatment of constipation with Duspatalin is not recommended for patients with kidney failure, children under 12 years of age, expectant mothers with a complicated pregnancy, breastfeeding, as well as people who have an increased susceptibility to antispasmodics.

When should Duspatalin be used?

Indications for taking the drug:

• Spasm-type pain localized in the epigastric region.
• Intestinal and biliary colic.
• Irritable bowel syndrome.
• Disturbances in the functioning of the gallbladder.
• Underwent surgery for resection of the gallbladder.
• Spasms of the smooth muscles of the digestive system against the background of pathologies of other organs (pain due to pancreatitis or cholecystitis).
• Pain caused by a functional disorder of the digestive system.
• Pain, discomfort and spasm in the intestines of a different etiology.

Analogues of Duspatalin

Description

The drug Duspatalin is produced in the Netherlands. Release form: white opaque capsules with a gelatin shell and granules as content. An alternative option is tablets.

The main component of the drug is mebeverine hydrochloride, which is part of the pharmacological group of myotropic antispasmodics. This substance has an antispasmodic effect, eliminating bloating and gas formation.

In addition, an improvement in the patient’s visual acuity is a pleasant “bonus”.

Excipients of the drug Duspatalin:

• magnesium stearate;
• ethyl acrylate copolymer;
• methyl methacrylate copolymer;
• methacrylic acid copolymer
• triacetin;
• hypromellose;
• talc.

Different forms of release of the drug require different methods of administration.

Duspatalin tablets

The tablet form is taken orally as a whole, without violating the integrity of the membrane, 30 minutes before a meal, washed down with a sufficient volume of water (at least 100 ml). The standard treatment regimen involves 125 mg (1 tablet) three times a day before main meals. The duration of treatment depends primarily on the doctor's prescription.

They focus on a stable therapeutic effect from Duspatalin (absence of pain, spastic phenomena). When a stable improvement in condition is achieved, it is recommended to gradually reduce the dose over 21-28 days, starting with twice a day (morning and evening). With a positive reaction from the body. At the last stage of dose reduction, the drug is taken only in the morning. A half dosage is possible by carefully breaking the tablet.

The phases of drug withdrawal depend on the patient’s well-being and can be adjusted either towards decreasing or increasing the period of dosage reduction. If undesirable symptoms resume, it is necessary to return to the previous stage of the Duspatalin regimen. Sudden cessation of use may cause withdrawal symptoms.

The capsule form of Duspatalin is taken twice a day with regular intervals between doses. The dosage is 1 capsule of Duspatalin 200 per dose. The drug in this form is taken 20 minutes before meals with a sufficient amount of water. Capsules must not be opened, broken, or consumed if the shell is damaged, as this leads to rapid absorption of a high dose of the drug into the blood and its removal from the body.

general characteristics

Duspatalin is produced in Holland. You can purchase the drug in the form of tablets of 135 g and capsules of 200 mg. The capsule form contains a larger amount of the main active ingredient compared to tablets. Due to this, you can achieve a long-lasting effect from taking the drug. Therefore, on the packaging of capsules there is the word “retard”, which means “slow down” in English.

The capsules are covered with a dense gelatin-based shell; each capsule contains white granules. Markings on capsules: “245”, “S”, “7”. You can purchase packages containing 10, 20, 30, 50, 60 and 90 capsules.

The tablets are round in shape and white in color. They can be purchased in the same quantities as capsules, and also in packs of 15, 40, 100 and 120 pieces.

Regardless of the release form, the main active ingredient remains the same - mebeverine. However, the auxiliary components in capsules and tablets are different. Their comparative characteristics are presented in the table.

Composition and action of Duspatalin

The active component of Duspatalin is mebeverine hydrochloride in a dosage of 135 mg, 200 mg. Other substances refer to auxiliary and shell elements. The drug is made in 2 dosage forms - white tablets, opaque capsules marked “245”.

The country of origin is the Netherlands, the patent holder is the pharmaceutical corporation Solvay Pharmaceutical. ATC code of the drug is A03AA04.

Mebeverine relieves spasm of intestinal smooth muscles, but does not affect its motility. The food bolus progresses at a normal physiological speed while taking the drug. Vitamins and nutrients are absorbed as usual.

The active component has an analgesic effect on the intestinal mucosa. The active substance Duspatalin does not cause constant relaxation of smooth muscles or hypotension of the colon.

Duspatalin is rapidly absorbed from the stomach. After administration, the drug undergoes prehydrolysis, does not enter the bloodstream and is not detected in the plasma. Metabolites are excreted in the urine and slightly in feces. Does not accumulate in tissues and is not addictive when used for constipation.